Article Details

Synthesis and Antibacterial Activity Screening of Pyrazole-Pyridine Derivatives | Original Article

Chetan Patil1 Sheetal Gulati2 H. S. Patel3 in Anusandhan (RNTUJ-AN) | Multidisciplinary Academic Research

ABSTRACT:

ABSTRACT

Fused heterocyclic compounds, 6-(5-(4-alkyl phenyl)furan-2-yl)-3-methyl-1-phenyl-1H- pyrazolo[3,4-b] pyridine-5-carbonitrile 3(a-e) were synthesized by the reaction of  3-Methyl-1-phenyl- 1H-pyrazol -5-amine(1) with 5-(4-alkylphenyl)furan- 2-carbaldehyde (2a-e) in presence of Acetoacetonitrile. The structures of all the compounds series (3a-e) were characterized by elemental and spectral studies. The compounds were also screened for antibacterial activity.